Free 11 Page Whitepaper: Learn How to Create Valuable Testing Data for Predicting Nasal Drug Absorption Using In Vitro Release Testing Methodologies
Nasal delivery has been explored as a potential alternative route for drugs with poor bioavailability and for the delivery of biosensitive and high molecular weight (MW) compounds such as proteins, peptides, steroids and vaccines.
In this whitepaper, you will learn:
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Factors influencing the absorption of drugs across the nasal epithelium
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How to overcome limitations of testosterone therapy, particularly with prolonged administration, through nasal administration
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How to use nasal membranes in Franz Cell testing
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What the key elements are for the design of an experimental nasal mucosa study
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How to evaluate your experiments through statistical calculations and data analysis
Considering the intrinsic value of intranasal route to overcome patient compliance concerns together with its pharmacokinetic advantages, it appears to be an appropriate route for the treatment of not only acute or chronic nasal diseases, but also for a range of acute or chronic conditions requiring considerable systemic drug exposure.