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Laboratory Testing Case Studies

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Development of Analytical Methods for Krill Oil and the Next Generation Source of Omega-3’s

 

Challenge: The objective of this project at Diteba was to develop methods for complete compositional analysis of Krill Oil. Such characterization included total lipid / fat content, phospholipids, free fatty acids, triglycerides, cholesterol esters, phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine, phosphatidylinositol, sphingomyelin, lysophosphatidylcholine, sterols, cholesterol, sigmasterol, sigmastanol, sitosterol, vitamin D-3, vitamin E, and carotenoids: canthaxanthin, astaxanthin.

Making Analytical Method Improvements to Fatty Acid Analysis

 

Challenge: The goal of this project was to develop efficient analytical methods for complete compositional analysis of lipid-based drug candidates.  Analytical method requirements included extraction, separation, identification and quantification.  Such work would support development of formulations which would include a small amount of a well accepted non-medicinal ingredient commonly used in food and drug products.  This undertaking focused on the development of a full fatty acid profile analysis of new lipid-based drug candidates targeted to formulate advanced products related to High Density Lipoprotein (HDL), often called "good cholesterol".

Develop Analytical Methods to Detect and Quantify Components in an Energy Soft Drink

 

Challenge: Diteba undertook research with the technological objective to develop a suitable procedure that was capable of detecting and quantifying all nine main components in an energy soft drink: caffeine, niacin, vitamin B6, pantothenic acid, riboflavin, vitamin B12, taurine, glucuronolactone and inositol. The procedure was intended for use in quality control testing and long-term stability testing of energy drinks.

Compendial Analytical Method Improvements for Ginsenosides & Flavonols

 

Challenge: The objective of this project was to develop simple, precise, rapid and reproducible analytical methods for the quantification of: a) major Ginsenosides in Panax quinquefolius extract; and b) Flavonols in Ginkgo Biloba extract and use these methods as quality control tools for commercial energy drink products.

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